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A 2025 systematic review in the American Journal of Sports Medicine confirmed preclinical support across tendon, ligament, muscle, and bone repair models while explicitly noting the absence of human clinical trial data (DOI: 10.1177/15563316251355551)

Thus, targeting this pathological feature in FA could be beneficial in alleviating brain iron accumulation, neuroinflammation, and neurodegeneration experienced by patients throughout the course of disease progression
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[PubMed 2565685] 1198
