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De Prins S, Koppen G, Jacobs G, et al

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2 Energy metabolism in neurons 2.1 Core characteristics and substrate preference of neuronal metabolism Neurons, in comparison to glial cells, maintain a higher energy level due to their continuous need to generate action potentials, synaptic potentials, and neurotransmitters

Furthermore, iHLOs enable patient-specific modeling, providing a platform for precision medicine tailored to individual genetic and pathological conditions 12,13