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Efficacy and safety of antioxidant treatment with alpha-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial

Log P values are important to evaluate the biological activity of compounds and estimate their permeability into cell membranes, particularly BBB, to exert its neurological effect [28,29]

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Conversely, MPC1 inhibition increases cell susceptibility to ferroptosis by preserving the mesenchymal properties of erPCCs, 101 indicating that MPC1 regulates ferroptosis in erPCCs through EMT