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This timeline corresponds to one complete skin cell turnover cycle

Importantly, the N-terminal catalytic GTPase-activating domain of ArfGAP1 (contained within residues 1136), serves as a poor substrate of LRRK2 (Figure 1E), consistent with a prior study (Xiong et al., 2012)

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Definition: Two products are bioequivalent if their rate and extent of absorption (bioavailability) do not show a significant difference when given at the same molar dose