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Besides the transcription factors, genistein-induced endoplasmic reticulum (ER) stress and its downstream targets are also reported to induce apoptosis in cancer

Activation of mTOR controls the loss of TCR in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation

In conclusion, there is a need for more targeted and specialized studies investigating specific signaling pathways involved in the GM-gut-brain axis, comparable to those conducted in mammalian models 5.2 Immune system Along with nutrient metabolism, and energy homeostasis, the GM has been generally recognized as a significant component of the intestinal mucosal immune system including regulation of innate and adaptive immunity ( Figure 1 )

The Massachusetts General Hospital published guidance emphasizing that the most effective strategy for preserving lean body mass during GLP-1 therapy involves combining a high-protein diet with consistent resistance exercise