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This study elucidates the role of the glutathione pathway in tracheal regeneration with aortic allografts, demonstrating its antioxidant-driven modulation of immune responses, extracellular matrix remodeling, and epithelial integration, advancing airway tissue engineering.
In response, we developed a multifunctional copper-based metal-organic framework (Cu-MOF) nanoparticle co-loaded with the STING agonist SR-717 and the glycolysis inhibitor 3-bromopyruvate (3-BP), coated with tumor cell membranes (termed BR@CuM@CM), to achieve integrated metabolic modulation and immune activation
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