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Dihexa: Limited human safety data warrants particular caution

It typically affects those with a genetic susceptibility , particularly HLA-DR/DQ gene variants

In vivo animal experiments showed that daily administration of NNMTi for 28 days to dietinduced obese (DIO) mice significantly upregulated the expression of lipolysisrelated genes (such as ATGL and HSL) and downregulated lipogenesisrelated genes (such as FAS and ACC), indicating that NNMTi effectively promotes fat breakdown and inhibits fat synthesis

Xu T, Lv Z, Chen Q, et al

Those with adequate levels often experience heightened focus and reduced risk of depression