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Risk factor-induced cell death processes and DAMP secretion It is well known that environmental, physiological and behavioral risk factors such as air pollution, high blood pressure, obesity, cholesterol levels, smoking or intensive alcohol consumption significantly contribute to the increased risk of cardiovascular and neurodegenerative diseases, diabetes and various organ-specific disorders

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doi: 10.1016/j.tem.2011.10.004 190 ChandrasekaranPWeiskirchenR

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354 Calcium signaling directly influences pathogenic Th17 cell inflammatory reactions through the regulation of mitochondrial function