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Antidepressants are also supposed to reduce this enzymatic activity in a dose-dependent style [118]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 467.Granger DN, Rutili G, McCord JM

STAT3, as an essential transcription factor, leads to the production of many cytokines in inflammatory processes of KCs [43, 44], which in turn not only have an impact on disturbing the oxidant-antioxidant system but also recruiting a more deal of immune cells into the skin lesions to perpetuate a positive feedback inflammatory loop and remodeling extracellular matrix [28, 36]

Hambright, W