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Elevated TFRC expression is associated with increased M2-macrophage infiltration and worse clinical outcomes, underscoring the role of iron competition as a key mechanism in tumor immune evasion [104]
doi:10.2174/138920009789375423 Lin SC, Ho CT, Chuo WH, Li S, WangTT, Lin CC

Sikiric P, Seiwerth S, et al

These resistant cells have also higher levels of FGF2 compared to the normal HUVAC, and following incubation with Bevacizumab, a further increase in FGF2 transcription and translation was observed alongside an increase in levels of FGFR1 and its phosphorylation
