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The pro-apoptotic effector proteins, including BAX, BAK, and BOK, can bind to the mitochondrial outer membrane during apoptosis, disrupting its integrity and promoting cell death

Published online July 5

Tartrazine (175-700 mg/kg for mice, 125-500 mg/kg for rats, p.o., once a day for 30 d) produces a few adverse effects in learning and memory functions in animals (mice and rats) [11]

Lancet 360 , 19031913 (2002)

Silybin comprises five hydroxyl functional groups, which are categorized based on their chemical characteristics into phenolic, secondary, and primary alcoholic groups 3
