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Despite high costs (the mean procedure cost amounts to PLN 5616) and the burden for the patient, LDL apheresis is still a very important complementary therapy for homozygous FH [259, 261263]
Low creatine and PCr levels in individuals with various types of muscular dystrophy have been shown to increase with creatine supplementation, leading to notable improvements in muscle strength [96]
L-carnitine (L-b-hydroxy-g-N-trimethylaminobutyric acid), an essential nutrient that converts fat into energy in mitochondria, has been shown to ameliorate liver damage
The hydrocarbon ends of lipids are non-polar and thus will not interact with water
In conclusion, loss of Rb probably sensitizes ferroptosis induced by sorafenib in HCC cells through increasing the mitochondrial production of ROS
