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Description
Further research is warranted to explore how other specific pathways implicated in PF pathogenesis, such as the PI3K/Akt signaling pathway, WNT/-catenin signaling pathway, JAK/STAT signaling pathway, and AMPK signaling pathway, interact with ferroptosis in regulating the development of PF

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It is unknown, however, whether the drastic difference between the concentration of Axin versus the other components applies universally, and whether different cells employ quantitative differences in the ratio of Axin and other components to shape their unique Wnt response kinetics (such as the speed and level of -catenin accumulation)

27, 219249.10.1038/sj.jcbfm.9600343 57 HertzL.SchousboeA.BoechlerN.MukerjiS.FedoroffS

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