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The authors suspected that a transiently positive AMA was in line with a prior hypotheses that oxidative stress-induced liver damage may lead to AMA production, and that without additional factors, atorvastatin exposure alone does not result in the development of primary biliary cholangitis

In hindsight we may have got good results because of a very slight (and accidental!) tweak in how we used it, but one that had big ramifications

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