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The specific mechanisms by which ferroptosis contributes to CHD pathophysiology require further elucidation, particularly regarding its interrelationship with other cell death pathways (e.g., apoptosis, necrosis)
Proc Natl Acad Sci U S A 102, 1554515550 (2005)
Among them, the thiol group (-SH) on the cysteine residue is the key active site through which glutathione performs antioxidant, detoxification, and other functions
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