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Being discussed by PCAC is a step in FDA's evaluation, not a final listing decision inclusion on a final bulks list is decided by FDA rulemaking informed by the committee [18]

The hOGG1 Cys/Cys genotype was found to be a possible risk factor for high-frequency hearing loss, and stratified analysis revealed it was also associated with risk factors such as years of work in noisy jobs, noise exposure level and smoking

The conditions that trigger oxidative stress include multiple complex factors such as mitochondrial damage, inflammation, apoptosis and oxidative damage to proteins, lipids and DNA ( 2 ) (157)

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