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These findings suggest that NAC-induced reduction in oxidative stress may disrupt redox-sensitive regulatory mechanisms within the HPA axis, impairing the negative feedback loop and promoting adrenal stimulation

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These effects are believed to be mediated, at least in part, via reductions in the amount of oxidative and nitrosative stress as acetaminophen intervention lowers the amount of superoxide and the abundance of oxidatively modified proteins (Wu et al., 2009a)

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Conflicts, unmet needs, or trauma can block desire regardless of biochemical support