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However, in the context of multi-cannabinoid therapy strategies, it is relevant to note that whether detrimental effects are seen appears to be dependent on age and the amount of THC co-administered

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GSSG generated in these processes can be either recycled to GSH by a NADPH-dependent reaction, catalyzed by GR 3 , or pumped out of the cell by ATP-dependent processes, with multidrug resistance-associated protein-1 (MRP-1) being the major pathway for GSSG efflux 33