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Approximately 3 to 4% absolute bioavailability via nasal route in adults, which is sufficient because the therapeutic dose is microgram-range and the target (V2 renal receptor) is highly sensitive
In addition, Fe 2+ promotes ROS production via the Fenton reaction, which is regarded as an amplified signal for insulin secretion [39, 40]
Without adequate circulation, follicles literally starve
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