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In contrast, there is a significant increase in M1 microglia (CD86+ve expression), which produce pro-inflammatory cytokines, ROS, and iNOS, contributing to neuronal injury and axonal damage (SMI-32+ve expression)

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Code availability Proteomics data were processed using open-source software: MaxQuant v 1.6 3.4 for DDA experiment ( DIA-NN v1.8 for DIA experiment ( Skyline v.23.1.0.380 ( for SRM and PRM experiments

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