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BPC-157 has shown consistent effects on tissue repair across multiple animal models, with proposed mechanisms including new blood vessel formation and modulation of growth factor signalling [11]

The peptide promotes angiogenesis by upregulating vascular endothelial growth factor (VEGF) expression and stimulating the formation of new blood vessels, which is critical for delivering nutrients and oxygen to healing tissues

Croatian researchers isolated the full, larger peptide BPC in 1998 from gastric juices and found the 15 amino acid sequence, BPC-157 to be the active part responsible for its clinical effects (the story of how it was discovered is fascinating, but that is a conversation for a different day if there is enough interest, let me know below)

[DOI] [PubMed] [Google Scholar] 19.Li, J