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In our recent study [166], a single dose and repeated doses of ceftriaxone, a beta-lactam antibiotic that acts by upregulating GLT-1 expression, thus increasing glutamate reuptake in the CNS [167,168,169], was tested for its ability to attenuate early-phase and late-phase tactile allodynia and cold hyperalgesia in oxaliplatin-treated mice

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Compliance was assessed by calculating the proportion of days on which individuals got the medication out of a maximum of 105 days