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Many patients continue with maintenance protocols at reduced frequency to sustain benefits

There is a lack of good quality clinical evidence that older people have a clinically significant difference in paracetamol metabolism or are at increased risk of toxicity at either therapeutic or supra-therapeutic doses

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3.2.4 Oxysterol modulation of GABA receptors Excitation can also be exacerbated by reduced GABAergic signaling (Shore et al., 2020

Moreover, their pH-responsive release characteristics can minimize interference with the intestinal microbiota, maintaining microbial homeostasis and achieving synergistic regulation of gastric mucosal protection and the microbiota