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Common subtypes include liquid chromatography-mass spectrometry (LC-MS), matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) (Yang and Chien, 2000), matrix-assisted laser desorption/ionization immunohistochemistry mass spectrometry (MALDI-IH-MS) (Taylor et al., 2025), and evaporative light scattering detection-assisted liquid chromatography-mass spectrometry (ELSD-LC-MS) (Cao et al., 2018)

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CUMS depression model mice treated with the compound Chinese medicine XiaoYao San for 2 weeks showed a decrease in hippocampal body weight, total iron, and ferrous iron content