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Motor development and disease progression in people with SMA is usually assessed using validated functional scales CHOP-INTEND (The Children's Hospital of Philadelphia Infant Test of Neuromuscular Disorders) or HINE (Hammersmith Infant Neurological Examination) in infants

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[DOI] [PubMed] [Google Scholar] 3.Tsunemi Y, Saeki H, Tamaki K

This transcriptional cascade takes 2472 hours to reach peak activity, meaning maximal melanin synthesis occurs days after the peptide itself has cleared
