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Commensal bacteria induced Th2 responses during the chronic phase exacerbate symptoms, emphasizing the pivotal role of microbial factors in shaping the immune landscape in chronic inflammatory conditions

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SSDC and ICH E3: Harmonized Reporting ICH E3 , which defines the structure and content of clinical study reports (CSRs), remains relevant when reporting trials that implement SSDC

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Anaphylactic reactions, which are severe allergic reactions that require immediate medical attention and can be life-threatening, with symptoms including chest tightness, itching, rash, trouble swallowing, swelling of the hands, face, or mouth, and trouble breathing