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6.1.2 WILLOW study (phase II clinical trial) 6.1.2.1 Study design and population The WILLOW study represented a pivotal Phase II clinical trial of brensocatib in bronchiectasis patients ( The study recruited 416 patients total, with 256 patients meeting inclusion criteria completing randomization, allocated to placebo group (87 patients), 10 mg brensocatib group (82 patients), and 25 mg brensocatib group (87 patients)

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In the first 6 months of life, breast-fed infants have a 62.86 times greater aluminum exposure from vaccines than from ingestion, formula-fed have an 11.58 times greater aluminum exposure, and soy formula-fed have a 3.76 times greater aluminum exposure

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Chronic diseases require continuous treatment for 7-14 days, once every 2 days