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Detection of mitochondrial DNA (mtDNA) mutations
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546,547 Olpasiran demonstrated a dose-dependent reduction in Lp(a) levels, with a single dose of 9 mg or higher reducing Lp(a) concentrations by over 90% for several months (NCT03626662)
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Further, 50 miRNA genes have been recognized in humans and it is hypothesized that about 500 human miRNA genes have yet to be discovered
