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27 Decreased expression of xCT leads to an increase in the rate of sulphur transfer from homocysteine to cysteine (through the trans-sulphuration branch of the methionine cycle), supporting the pivotal role of xCT in cyst(e)ine transport and cysteine provision

As previously mentioned, oxidative stress and the depletion of endogenous antioxidants play important roles in the etiology of neurodegenerative disorders, including MS

[DOI] [PubMed] [Google Scholar] 82.Kunutsor SK, Dey RS, Laukkanen JA

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Bagot RC, Tse YC, Nguyen H-B, Wong AS, Meaney MJ, Wong TP