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[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Haas JT, Miao J, Chanda D, Wang Y, Zhao E, Haas ME, Hirschey M, Vaitheesvaran B, Farese RV Jr, Kurland IJ, Graham M, Crooke R, Foufelle F, Biddinger SB

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The pain reduction induced by ALC may be mediated by both a neuroprotective and a central anti-nociceptive mechanism

and (4) with no history of cerebrovascular disease

Unfortunately, characterization of disease severity in patients included in several studies in this review is scarce, and survival time is only accounted for in two trials [14,33]