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For example, inhibition of FAO in human glioblastoma cells by etomoxir, a CPTI inhibitor, impairs NADPH production and increases ROS, resulting in ATP depletion and cell death
KG is required for the activity of KG-dependent dioxygenases 2 (KGDDs), and previous work has focused almost exclusively on the demethylase functions of KGDD
Die Dosierung bewegt sich im wirksamen Bereich, sodass beide Nhrstoffe ihre Funktion erfllen knnen
doi: 10.1016/j.molcel.2014.03.012 208 PciennikowskaAHromada-JudyckaABorzckaKKwiatkowskaK
