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Ongoing and Completed Clinical Trials for the Management of Respiratory Diseases Based on Cytokine Therapy The data for ongoing and completed clinical trials investigating the management of various respiratory diseases based on cytokine therapy are presented in Table 4 with the disease conditions and interventions

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NRF2 is thought to indirectly enhance supersulfide production by increasing cellular cysteine via xCT upregulation [316], so the radical scavenging by supersulfides represents another downstream mechanism of NRF2-mediated ferroptosis prevention

Figure 4.2: Tyrosine can be produced from phenylalanine metabolism and is required for the production of melanin and catecholamines