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Description
The pharmacological effects of metformin have been shown to target the insulin-like growth factor (IGF), AMP-activated protein kinase (AMPK), phosphatidylinositol 3-kinase (PI3K)/AKT, MAPK, NF-B, and other signal transduction pathways, highlighting its potential in the treatment of gynecological disorders
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doi: 10.1086/665457
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From a basic risk management perspective, stacking is worse than using any single compound alone
