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[PubMed: 1088963] 448
L-arginine supplements are generally not recommended for people who have: kidney disease low blood pressure (hypotension) guanidinoacetate methyltransferase deficiency, an inherited condition that impacts arginine metabolism L-arginine may also interact with medications like those used to treat high blood pressure
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doi: 10.1093/jn/123.6.1054
Neurological Problems: Especially in people over 50 years of age, constipation can be a cause for concern because of the effects that nerves play in connection to the gut
