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Mechanism of PRP in Osteoarthritis PRP contains growth factors and cytokines that promote cartilage repair and modulate inflammation, including: Platelet-derived growth factor (PDGF): Stimulates chondrocyte proliferation and matrix synthesis Transforming growth factor-beta (TGF-): Encourages cartilage regeneration and reduces catabolic activity Vascular endothelial growth factor (VEGF): Enhances microcirculation to support healing Interleukin-1 receptor antagonist (IL-1Ra): Suppresses pro-inflammatory cytokines that degrade cartilage These biological effects differentiate PRP from corticosteroids , which primarily suppress symptoms but accelerate cartilage degradation with repeated use (PMID: 30404447)

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[DOI] [PubMed] [Google Scholar] 115.Zorov, D

Lu H-T, Huang G-Y, Chang W-J et al (2022) Modification of chitosan nanofibers with CuS and fucoidan for antibacterial and bone tissue engineering applications

Take it after consulting a doctor if you are on any type of medication