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Fisetin deters cell proliferation, induces apoptosis, alleviates oxidative stress and inflammation in human cancer cells, HeLa

Li, X., Egervari, G., Wang, Y., Berger, S

Severe oxidative stress can overcome the ability of the cell to reduce GSSG to GSH leading to accumulation of GSSG

We discuss the potential implications of the involvement of AR interactors in multiple AR-dependent (non-)transcriptional cellular processes for alternative CaP treatment strategies that disrupt AR-coregulator interplay to inhibit AR-dependent transcription when AR ligand-deprivation has failed