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The authors noted a non-significant trend towards a lower incidence of liver transplantation in the treatment group and a significant increase in the incidence of nausea and vomiting as the main side effect

This, in turn, triggers the formation of a hetero-oligomeric cysteine synthase complex (CSC) with O -acetylserine(thiol)lyase B, a process that activates sulfur assimilation and the accumulation of sulfur-containing metabolites such as GSH (Watanabe et al

Data from various subgroup analyses further support the benefits of NAC in terms of symptom severity, functioning, response rate, symptom remission, and quality of life [155-158]

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apologies if Ive missed it