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Formation of flavonoid metabolons: functional significance of proteinprotein interactions and impact on flavonoid chemodiversity

[DOI] [PubMed] [Google Scholar] Giera M

Metabolic signaling refers to the messages cells use to manage energy use and storagefor example, how cells decide when to use glucose, store fuel, or shift energy production pathways in response to changing conditions in an experimental model

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Critical challenges included insufficient sample size reducing statistical power, reliance on self-reported exposure data introducing recall bias, and inadequate control for confounding factors such as smoking and alcohol consumption