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Herein, an increase in xanthine levels and a decrease in XDH expression in cells under continuous tamoxifen treatment was noted indicating a switch from xanthine oxidation to the purine salvage pathway and thus increased purine nucleoside synthesis

Vieira BRM, Guermandi II, Bellot MS, Camargo-dosSantos B, FaveroNeto J, Giaquinto PC
Ortega-Hernandez, O

However, that ratio drops to 10 or less in susceptible cells exposed to oxidative stress

30, 3411.e73423.e7
