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Generally, gentle mobility work and supportive therapies are considered complementary

According to NICE Clinical Knowledge Summaries and the British National Formulary (BNF), the recommended treatment regimens are: For patients without neurological involvement : Initial treatment: hydroxocobalamin 1 mg intramuscularly three times a week for 2 weeks Maintenance: hydroxocobalamin 1 mg intramuscularly every 3 months for life For patients with neurological involvement : Initial treatment: hydroxocobalamin 1 mg intramuscularly on alternate days until no further improvement Maintenance: hydroxocobalamin 1 mg intramuscularly every 2 months for life If neurological symptoms are present, treatment should be started urgently to prevent irreversible damage

Give it a few weeks and discuss any changes (or lack thereof) with your healthcare provider at follow-up

External stimuli-mediated BBB disruption To regulate the BBB permeability, external stimuli-mediated BBB disruption based on the energy conversion materials has been widely explored