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Calculate the sample standard deviation using (n-1) degrees of freedom, o, of six or more measurements, and express the repeatability as a percentage (%) relative to the mean value of the osmolality standard, X 0 : R % = 100 / X 0 The precision of the instrument, in mOsmol/kg, at the osmolality of a test solution being analyzed is: R osm = (R % /100) X where X is the mean value for the test solution

Patients with Mitochondrial Disease: There is an increased risk of valproate-induced acute liver failure and resultant deaths in patients with hereditary neurometabolic syndromes caused by DNA mutations of the mitochondrial DNA Polymerase (POLG) gene (e.g