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These events collectively result in mitochondrial dysfunction, elevated ROS, and impaired protein clearance, the triad that drives S misfolding and aggregation

Microinfusion is the bridge

In addition to the skeleton of lyngbyabellins, this molecule also exhibited an N,N -dimethylvaline side chain similar to dolastatin 10 (Choi et al

Peptide degradation follows first-order kinetics, meaning each hour at elevated temperature compounds previous damage