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doi: 10.1164/rccm.200502-180OC
Pooled estimates were calculated with the random-effects model, considering that the patients came from different populations
They are more prevalent in dogs (2% of all neuroepithelial tumors), but are reported in cats, horses, and cattle
Amasene et al., 2019)
Metformin also has indirect antitumoral effects due to its ability to reduce insulin and insulin-like growth factor 1 (IGF-1) levels and to influence metabolic pathways such as lipid metabolism and inflammation [15], which are known to promote HCC tumour growth and proliferation [162,163,164,165]
