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B7-33 is primarily studied for its anti-fibrotic effects, meaning it may help reduce excessive scarring and tissue hardening, common outcomes of chronic inflammation

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The authors reported modestly higher objective sleep efficiency and shorter sleep latency in the DSIP arm versus placebo, but subjective sleep-quality measures did not improve and the authors themselves concluded that short-term treatment of chronic insomnia with DSIP is not likely to be of major therapeutic benefit. That is the strongest controlled human sleep study in the literature, and its conclusion is negative to modest

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Stem Cells Dayt Ohio 33:13201332 [DOI] [PMC free article] [PubMed] [Google Scholar] Jia L et al (2019) Vitamin B12 inhibits -synuclein fibrillogenesis and protects against amyloid-induced cytotoxicity