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In addition to the complexity of the PDHc at the level of the total number of protein subunits (30 subunits of E1, 60 subunits of E2, and 12 subunits of E3), the full activity of the PDHc requires five different vitamin-derived coenzymes: CoASH, NAD + , FAD, lipoic acid, and thiamine pyrophosphate (TPP)

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improve the function of intestinal cells, and positively impact bowel movements[14]
Commonly used circulating biomarkers include oxidized low-density lipoprotein (ox-LDL), AGE, and oxidized thiol compounds
