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Why Adjuvant Therapy Is Necessary Even after apparently complete surgical resection of a primary tumor, a subset of patients harbor occult residual disease in the form of micrometastases clusters of cancer cells too small to detect on imaging but capable of establishing distant metastases over time

Chemical inhibitors targeting these proteins have been extensively studied as candidate ferroptosis inducers

The schedule is daily for weeks 14, five times a week for weeks 58, then two or three times a week for ongoing maintenance

Individuals with bone marrow disorders 10 , 11

Key agents are summarized in Table 2
