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In vitro and in silico studies of secang wood ( Caesalpinia sappan L.) extracts and Brazilin as natural phosphodiesterase-1 (PDE1) inhibitor for herbal cognitive enhancer development

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[DOI] [PMC free article] [PubMed] [Google Scholar] 122.Shaughnessy D.T., McAllister K., Worth L., Haugen A.C., Meyer J.N., Domann F.E., Houten B.V., Mostoslavsky R., Bultman S.J., Baccarelli A.A., et al

However, this result must be interpreted with considerable caution, as it may be largely due to confounding by indication 20 and differences in the underlying patient populations