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Prominent non-enzymatic AOXs include vitamins such as Vitamin C and Vitamin E (17, 20, 21), glutathione (22, 23), coenzyme Q10 (2427), carotenoids (e.g., beta-carotene, lycopene) (28), polyphenols (29), and trace elements like selenium and zinc (24, 30)

LSECs also influence macrophage phenotypes through paracrine signaling of IL-10 and TGF- [183]

Choi ML, Chappard A, Singh BP, Maclachlan C, Rodrigues M, Fedotova EI, Berezhnov AV, De S, Peddie CJ, Athauda D, Virdi GS, Zhang W, Evans JR, Wernick AI, Zanjani ZS, Angelova PR, Esteras N, Vinokurov AY, Morris K, Jeacock K, Tosatto L, Little D, Gissen P, Clarke DJ, Kunath T, Collinson L, Klenerman D, Abramov AY, Horrocks MH, Gandhi S (2022) Pathological structural conversion of -synuclein at the mitochondria induces neuronal toxicity

On the other hand, it is also of great significance to discover the effective active metabolites in many chemical metabolites of TMMM, and even to discover potential new drugs

Barrier models maintaining a resilient cellular barrier in lab settings (frequently studied in epithelial/monolayer assays)