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Every batch is independently lab tested for identity, purity and potency

Sirtuins also perform other post-translational reactions such as NAD + -dependent desuccinylation, diacylation, and demalonylation, and are important in regulating metabolism, allowing metabolic plasticity 7

The high NAD+ base carries a concentrated MOTS-c and 5-Amino-1MQ pairing, making it primarily a concentrated MOTS-c / 5-Amino-1MQ blend on an NAD+ foundation

5-Amino-1MQ has viable oral bioavailability due to its small molecular weight (177.21 Da), making it suitable for capsule administration

Further experience with the use of anti-CD38 antibodies in RRMM after prior treatment with daratumumab will stem from a current phase Ib trial of SC isatuximab in combination with Pd (NCT04045795) and for daratumumab from a phase II study in combination with Kd (NCT03871829)