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Nutrients 13 , 758 (2021)
Compared with the cantuzumab mertansine (huC242-DM1) containing a cleavable disulfide linker, the huC242-SMCC-DM1 is efficacious only against tumors in which all proliferating cells express the target antigen, and displayed significantly lower in vivo activity in multiple xenograft tumor models (Figure 4) [47]
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The marked enhancement of mTORC1 signaling by CHX was also observed in the control cells (Fig
Aust N Z J Psychiatry 2021;55:196-206
